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TSH consistently rising and T4 low normal - Should I begin medication? I have TSH labs over 5 years and my TSH is consistently rising. It is now just over 2.75. My T4 and free thyroxine index are both low normal (at the lower end of the range). I'm experiencing fatigue, weight gain, and difficulty sleeping and concentrating. I had part of my thyroid removed 14 years ago. I've read that rising TSH increases your risk of goiter recurrence. Would it be practical to begin medication now with the goal of bringing the TSH down and the T4 a little higher in the normal range?

LouieAP replied: "I assume that the medication you're referring to is Synthroid to boost your thyroid level. It is not surprising that your TSH is rising after partial thyroid resection since the presence of T3 and T4 in the blood reduces the amount of TSH released by your pituitary gland. All your symptoms and history certainly do suggest a primary hypothyroidism, and Synthroid (or equivalent medication) would be indicated for this condition. Has your doctor given you any reason to not begin a treatment regimen?"

sweetie_pie1618 replied: "Yea you should definately be on medication. Try talking to your doctor again about your concerns, if they do not listen, then ask for a second opinion. Just be persistent keep asking for tests."

Please explain to me the results of my Thyroid Panel with TSH? Could I have Hypothyroidism with these results? TSH - 2.225 Thyroxine (T4) 7.1 T3 Uptake - 26% Free Thyroxine Index 1.8 My mom, aunt and grandmother all have a thyroid problem. I have symptoms - espcially low concentration & weight gain - impossible to lose even when eating right & exercise.

Baby Olivia On The Way replied: "you need to talk to your doc with these results. i was feeling very lethargic and was diagnosed w/ mild hypothroidism at 18. i only take the lowest dose which is .25mcg every morning........ when you get it under control its nothing much to worry about. ps my mom had hypothroidism"

rak replied: "I work in a hospital lab, and your numbers are all normal, in fact they are perfect. I am sorry if that's not what you wanted to hear :( It is not the answer to your current symptoms. You might have something else going on that is causing the weight gain and lack of concentration. Other things could explain those symptoms...have you ever been tested for polycystic ovary syndrome or had cortisol testing? Because your mom and grandma have thyroid problems, it is something you might have a problem with in the future especially when you hit menopause age. But for now, your numbers are great! Your thyroid is functioning properly. Hope that helps. Anymore questions, feel free to email me. Edit-DNA, where did you get your range for TSH from? Our range is 0.500-4.68 being normal. Of course, maybe the ranges you know are from are from a different insrument. Let me know if you can. Thanks so much!"

DNA replied: "Yes, its possible you could be in the early stages of the condition. A TSH over 2.0 is not normal, however must doctors wil not treat until its over 3.0 and many others over 5.5. Was this a morning thyroid test? Thyroid testing should always be done first thing in the morning only because the TSH is near its high point then. I'll put a couple of related links below. BTW, my first TSH was 2.6 (afternoon reading) I was told I did not have a thyroid problem. Almost a year later symptoms got more severe and the next TSH test was 6.8 and I got diagnosed. Next time you test in the morning, get a TSH, Free T4, Free T3, and an antibody test."

High TSH and hypothyroid problems? About 2 years ago I was diagnosed with hypothyroid disease by some accidental blood exam. My sister was hypo too and a lot of symptoms started to make sense. God knows for how long I had been hypo. However, now I have 2 hypo sisters and they have troubles loosing weight in spite of their treatment. I (hypo too) however am still very slim and have troubles gaining weight! I am 45 y.o. and my highest weight has been 69kg, now I am down to almost 64kg. I regularly (1/year) have blood checks for my hypo: T4 Free Thyroxine: 24 JAN 2008 15.0 07 OCT 2008 16.9 19 MAR 2009 15.8 TSH (Thyroid Stimulating Hormone) 07 OCT 2008 3.1 14 OCT 2008 2.9 19 MAR 2009 4.2 In my last exam (19mar) the T4 is apparently still regulated but the TSH came out marked (!) as higher than normal (4.2) but the general practitioner did not mention anything. The problem is that for the past month or so I have had off/on pains on the (left) side of my neck (near the windpipe) and in the past 2 days the pain has been more annoying than usual, It feels kind of swollen there, more on the base of the neck than higher up. I have not gone to my GP because that woman tends to ignore my complains. My hypo was actually "discovered" by her replacement when she was on holidays (I wish she stays on holidays forever). So, is this higher TSH related to that pain/swelling on the side of the neck? I live in Europe but it could be that my diet is low on Iodine. I am trying to use iodized salt but with care (don't want high blood pressure). My treatment has been limited to a single pill of Thyrax Duotab (Levothyroxine sodium) of 0.025mg per day.

jimmymae2000 replied: "Normal TSH is .5 to 5.0, you didn't mention your dose of centroid."

stealthwind replied: "This website can answer a lot of your questions: The current TSH range is (0.3-3.0) TSH ideally should be "almost zero". Why? Because TSH is a hrmone put out by the pituitary gland to signal the thyroid to produce more thyroid hormones. Obviously when there are "enough" thyroid hormones available, the TSH will be low. YOUR TSH is too high. Also the proper other tests are FREE T3 and FREE T4, and they should be near the top of their ranges, or a bit above, with the Free T3 being slightly higher than the Free T4. If you're in an area of the country that is considered in "the goiter belt", your thyroid issues are likely due to iodine deficiency. An iodine deficiency will affect the thyroid and the entire body. The pain in your neck sounds like it in the area of your thyroid, and it could be our thyroid is "complaining" and wanting more body iodine to produce thyroid hormones for you. If you don't have enough iodine in your body, your thyroid can not produce the proper amount of thyroid hormones. Here are sites about iodine: I hope this info helps"

lab rat replied: "(Please ignore stealthwind - that information is incorrect) I presume you're on thyroxine? Usually if someone is taking T4 and their TSH is a little high, that's a sign the dose needs increasing. Your TSH is consistently towards the top end of normal and your T4 is in the middle of the normal range - most people on treatment are treated to give a normal or low-normal TSH and a high-normal T4. But obviously it's not just based on numbers - maybe your GP didn't feel you needed an increased dose if you're not having hypothyroid symptoms and you're not overweight. I wouldn't like to say what the pain in your neck is - it could be a thyroid issue and it's worth getting it checked out. However I think it's unlikely that it would affect the TSH if you are taking thyroxine. TSH is produced by the pituitary gland in response to the thyroxine level in your blood. Since you are presumably taking thyroxine, the TSH just reflects the T4 dose you are on."

need a doctor to answer??? here's the result of my thyroid panel...but i don't understand this...pls help...triidothyronine (T3) 1.48H ng/ml; thyroxine(T4) 8.36ug/dl; T-uptake 0.87; TSH 0.234L uIU/ml; Free triidothyronine 4.04H pg/ml; Free thyroxine(FT4) 0.78 ng/dl; Free thyroxine index 9.61...tnx

J replied: "The first number you care about is TSH. TSH, or Thyroid Stimulation hormone, determines whether your thyroid is overactive or underactive. Your brain makes TSH based on how much your thyroid hormone status. If your body needs more thyroid hormone, your brain makes more TSH, so it is high. If your body has too much thyroid hormone, your brain makes less TSH. In your case, your TSH is low (normal is about 0.5 to 5, optimally between 1-2), so you are overactive thyroid, or hyperthyroid, by definition. Your T4 is normal. However, you have too much T3, which is the active form of thyroid hormone. Your thyroid gland makes makes T4, which flows around blood. Your tissue will take T4 and convert it to T3. There are 2 types of thyroid hormone. Synthroid, Levothyroxine, etc, are T4. Cytomel is T3. Normally, when someone is hyperthyroid, his T4 and T3 are both elevated. My assumption is that you are taking thyroid medication, maybe T3. You need to ask your doctor to adjust your dose."

need a doctor to explain??? here's the result of my thyroid panel...but i don't understand this...pls help...triidothyronine (T3) 1.48H ng/ml; thyroxine(T4) 8.36ug/dl; T-uptake 0.87; TSH 0.234L uIU/ml; Free triidothyronine 4.04H pg/ml; Free thyroxine(FT4) 0.78 ng/dl; Free thyroxine index 9.61...tnx

medstudent050 replied: "T3 is pretty normal. T4 is normal. T-Uptake (not sure sorry) TSH looks low. free TTH is normal. FT4 is good. FTI is good. I am not qualified but maybe slight hyperthyroidism. Ask your doc."

Calling Endocrine Experts!!!! Bloodwork interpretation!!!!!? DHEA - 507 HIGH BIOTIN VIT B7 - 179 LOW H. PYLORI - 1.28 HIGH VITAMIN D- 15.7 LOW TSH is 2.155 (ref 0.450-4.500) T3 Uptake is 28 (Ref 24-39) Free Thyroxine Index is 2.5 (ref 1.2-4.9) Antithyroglobulin AB 20 (ref 0-40) Thyroid Peroxidase TPO 10 (ref 0-34) Thyroxine (T4) 8.9 (ref 4.5-12) Ferritin 14 FSH Serum 1.1 Antinuclear Antibodies Direct 22 hCG Beta subunit Qnt Serum 2 LH 2.3 Prolactin 7.0

william.lonn replied: "Oh shit, you serious? Dude i am sorry well try to make the best of life, eh?"

Nate L replied: "H. Pylori -- possible bacterial infection. DHEA high -- possible adrenal dysfunction. Thyroid markers are fine. What am I, a Doctor? Call your Doctor and talk to a nurse."

Blood Tests Results? Thyroid Disease? Female 24 very tired. DHEA - 507 HIGH BIOTIN VIT B7 - 179 LOW H. PYLORI - 1.28 HIGH VITAMIN D- 15.7 LOW TSH is 2.155 (ref 0.450-4.500) T3 Uptake is 28 (Ref 24-39) Free Thyroxine Index is 2.5 (ref 1.2-4.9) Antithyroglobulin AB 20 (ref 0-40) Thyroid Peroxidase TPO 10 (ref 0-34) Thyroxine (T4) 8.9 (ref 4.5-12) Ferritin 14 FSH Serum 1.1 Antinuclear Antibodies Direct 22 hCG Beta subunit Qnt Serum 2 LH 2.3 Prolactin 7.0

Tulip M replied: "u need thyroxine to help fix ur thyroid or u will definately feel tired im guessing u have hypo thired"

sbl09 replied: "idk how to read that but it sounds like you have hypothyroid condition. you just take a pill (like the person said above, thyroxine or synthroid or levothyroxin) every day and that should help."

thyroid levels??? i need some help? well i want to know if some are too low. or too high. Ive been on synthroid (lowest dose .0025) for a month and a half. TSH - 3.637 T4 Free direct - 1.23 ng/dl Thyroxine (T4) - 7.7 ug/dl T3 Uptake - 0.84 are my levels ok? will they keep getting better with synthroid? i before synthroid my tsh was 5.6 and it dropped in one month, as you can see.

sel replied: "These levels look fine. Without getting into the complicated details why, for practical consideration the only number of interest to you (or to your doctor) here is the TSH. The correct dose of synthroid is the lowest dose that will make the patients TSH normal - and 3.6 is solidly normal (0.5 - 5.0 is the common range for normal.) In fact, many folks would argue that TSH of 5.6 is so close to normal that if a person were experiencing no symptoms (google hypothyroidism for a list of possible symptoms) they would not even need to take synthroid at all. FYI the other thyroid tests are of use/interest only in cases where the TSH is too low, much too high, or, if high, cannot be made normal by a typical dose of synthroid."

flika replied: "Looks good and the Synthroid is doing what it is supposed to do... TSH normal range: 0.3-3.0 (yours is much better.) This range is used by many physicians. (Some still use a normal range of 0.5 to 5.0) T4 Free normal range: 0.7-2.0 T4 Total normal range: 4.5-12.5 T3 Free normal range: 230-420 T3 Total normal range: 60-181"

Mia replied: "I started the same dosage as you're on about six weeks ago. I will go and recheck my levels again in two days. My starting TSH was 3.75, my T4 was 1.0, and my T3 Total was 91. My MD said she would like to get my TSH under 2.0 (I personally want it even lower, like a 1.0, which normal, healthy people have), and she wants to see my T3 increase up over 100. She said that my next lab results will reveal whether or not the Synthroid(T4) is converting into T3. If it doesn't then she will start me on Cytomel (T3). If you do some research, you will find that many people can't convert T4 to T3 and need a supplement. On my next visit, I plan on asking about adding Selenium because it is known to help with conversion. I'm finding tons of good info/advice about thyroid issues at this site: "

confused about T4 , T3......? I've been taking Levothyroxine but it's been making me feel weird after a couple months of taking it, and i just noticed on my results from before I got put on the med that my thyroxine -free was in the normal range, so does this mean I need T3 instead of the Levothyroxine meds they gave me??? seems like i've been taking this for nothing..

R Jimlad replied: "T4 is made from T3 (and that from T2, and that T1) in your thyroid. T3 itself is very potently active, but there's so little of it free that essentially T4 (thyroxine) is what you run on. So the answer is - its more or less the same stuff, and replacing Thyroxine is the best, and most normal way. If you were to be given T3 (which I dont beleive is even made up as a drug, but could be wrong), it would be either be made into T4 by the body, or be way way too strong."

Tsh levels WAY high & synthroid help? Been on synthroid for years at 25 MCG, this kept my TSH at about 5-8. 2 years ago my TSH suddendly started going up, med slowly increased. 1 year ago, my TSH was 55.772, T4 6.2, t3uptake 29, Free thyroxine index 7.8 so everything was normal except my TSH, the doctor upped ,my synthroid to 100mcg 1 year ago. Today the TSH is higher again at 73.224, but the T3, t3 uptake & free index are all perfecty normal. He wants to leave my synthroid at 100 mcg again this year since the actual thyroid is normal. I told him I would really like to slowly increase it to 112mcg & then probably 125mcg in 3 months if the TSH was still high. I am lucky sort of as I do have dry skin in cold weather, dry hair, (But normally dry, course & curly all my life). Energy is ok as long as I do get 8 hours sleep, any less sleep & I am a basket case. Stress & being rushed & hurried & I get really anxious & to the point of panic, dizzy etc. Do I need to get a second opinion? Or is my synthroid level ok still? If your Tsh is high, your thyroid is usually low. THS is thyroid stimulation hormone. Tsh is produced to try to make your thyroid stimulated to produce more. Thyroid test numbers are confusing as a high tsh means low thyroid for this reason.

N Jo replied: "Definitely get a second opinion. Your TSH is way too high! Once you get your TSH in tact, you will have more energy and feel a LOT better. Find an endocrinologist that has good experience with thyroid issues. Many endocrinologists treat diabetes patients and are just so/so when it comes to thyroid. Also, get a copy of your records and take them with you to your second opinion appointment."

onlymatch4u replied: "I used to take synthroid and now I'm not taking any at all. It has taken me a lot of time to get to this point. Synthroid is very bad for you and is the doctor's easy way out of a problem they just don't want to spend time figuring out. It leaves you with a thyroid that is being slowly killed by the synthroid, dependent upon it for the rest of your life, and chained to the doctor each year who loves seeing you walk through his door and looking at your blood samples. There are many reasons thyroid glands slow down and you need to go to a real doctor that will take the time to figure it out and not some 15 minute whiz bang guy that just wants your money and does not care about what that drug is doing to you. The TSH test is just not sensitive enough and is only the tip of the ice berg tests that need to be done to figure out what is really going on with you. I found out that I was simply deficient in iodine that was causing my problem and when I fixed that, I fixed my thyroid. But the Synthroid did a lot of damage and it took several months to fix the problem once I figured it out. Additionally, I had a severe head trauma that blocked my 20th meridian that was reflexing to my thyroid, keeping the energy level low. I fixed that by clearing my lymph system with herbs and my 20th meridian cleared with very special clay packs. The reason you are a "basket case" when you don't get sleep is because your body needs to get at least 5 hours of uninterrupted sleep to allow you to go into a REM sleep. Without getting to the REM state, your adrenal glands do not get recharged and your energy level the next day will be greatly affected, and you will feel dizzy if you stand up quickly. I also suggest STRONGLY, that you test yourself for iodine deficiency. Paint a patch of "tincture of iodine" on your chest about the size of a golf ball. If the stain goes away before 24 hours, you are deficient. The thyroid only uses about 3% of the iodine you take in and the rest of your organs use the rest, including your skin. Anything with Fluoride of any kind in it will make you deficient in iodine. ALL soy products that are not fermented will slow your thyroid greatly. Look at your literature in the synthroid packet and you will see they tell you to avoid SOY! I believe you should find a doctor that cares and dump the bozo you are going to. good luck to you."

mountaingal replied: "This makes no sense. If you have a high TSH (thyroid stimulating hormone), then you should have plenty of hormone in your blood. Synthroid is what y ou take to increase the thyroid. If you are allready high in hormone, why would you want to increase it? If you have too much Synthroid in your system you will feel panicy/wired-like too much coffee/very agitated/ unable to sleep or relax. Get to an endocrinologist or at the very least an internalist."

DNA replied: "You need a different doctor. Once on thyroid treatment, the morning TSH should be below 2.0. Keeping you at a TSH of 5-8 is poor care. The other tests your doctor did don't tell much. What you need is a free t4 and free t3. These tests show the actual amount of these hormones avaiable for use. A TSH over 2.0 could be causing elevated cholesterol levels and heart problemsdone the road. Links below"

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